Appendix 9: Numerical score sheet for assessing neonatal genetically modified rodents
This is Appendix 9 of the Code of Practice for the Housing and Care of Laboratory Mice, Rats, Guinea Pigs and Rabbits.
AEC Project #: | Animal ID/Strain*: |
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Investigator: | Date: |
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Observer: | Age (days): |
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Appearance/colour | Normal (pink) | 0 |
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Pink/blue abdomen | 1 |
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Pink/pale extremities | 2 |
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Blue/pale | 3 |
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Surface temperature | Warm | 0 |
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Intermediate | 1 |
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Cold | 2 |
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Natural activity | Wriggling ++ | 0 |
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Wriggling + | 1 |
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+/- | 2 |
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Still | 3 |
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Reflexes/respond to touch | +++ righting reflex | 0 |
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++ righting reflex | 1 |
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+ | 2 |
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- | 3 |
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Milk in stomach | ++ | 0 |
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+ | 1 |
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- | 2 |
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TOTAL SCORE (Neonate) | 0-13 |
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Parameter (mother) | NB Include Milk Score |
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Nest building | Good nest making | 0 |
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Some nest making | 1 |
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No nest | 2 |
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Retrieval of young | Always | 0 |
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Sometimes | 1 |
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Never | 2 |
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TOTAL SCORE (Mother) | 0-6 |
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use * to identify new GM strain
Judgement: neonate
0–4 = Good
5–8 = Fair
9–12 = Poor
Always assess maternal factors as well. Maternal score 5 to 6 = will these animals need fostering?
Comments:
Actions (if required):