Appendix 9: Numerical score sheet for assessing neonatal genetically modified rodents

This is Appendix 9 of the Code of Practice for the Housing and Care of Laboratory Mice, Rats, Guinea Pigs and Rabbits.

AEC Project #:

Animal ID/Strain*:

Investigator:

Date:

Observer:

Age (days):

Appearance/colour

Normal (pink)

0

 

Pink/blue abdomen

1

 

Pink/pale extremities

2

 

Blue/pale

3

 

Surface temperature

Warm

0

 

Intermediate

1

 

Cold

2

 

Natural activity

Wriggling ++

0

 

Wriggling +

1

 

+/-

2

 

Still

3

 

Reflexes/respond to touch

+++ righting reflex

0

 

++ righting reflex

1

 

+

2

 

-

3

 

 

Milk in stomach

++

0

 

+

1

 

-

2

 

TOTAL SCORE (Neonate)

0-13

  

Parameter (mother)

NB Include Milk Score

  

Nest building

Good nest making

0

 

Some nest making

1

 

No nest

2

 

Retrieval of young

Always

0

 

Sometimes

1

 

Never

2

 

TOTAL SCORE (Mother)

0-6

  

 

use * to identify new GM strain

Judgement: neonate
0–4 = Good
5–8 = Fair
9–12 = Poor

Always assess maternal factors as well. Maternal score 5 to 6 = will these animals need fostering?

Comments:

Actions (if required):

Page last updated: 21 Dec 2022